Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch_repos |
| Phenotype | phenotype_absentNotch_versus_wtNotch.cls#absentNotch_versus_wtNotch_repos |
| Upregulated in class | wtNotch |
| GeneSet | HUMANCYC_SUPERPATHWAY OF GLYCOLYSIS, PYRUVATE DEHYDROGENASE, TCA, AND GLYOXYLATE BYPASS |
| Enrichment Score (ES) | -0.7844763 |
| Normalized Enrichment Score (NES) | -1.6167834 |
| Nominal p-value | 0.0044444446 |
| FDR q-value | 0.111982256 |
| FWER p-Value | 0.885 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | DLST | 2320722 | 457 | 0.541 | 0.0163 | No | ||
| 2 | IDH2 | 2680397 | 722 | 0.370 | 0.0301 | No | ||
| 3 | ACO2 | 4230600 | 1824 | 0.144 | -0.0183 | No | ||
| 4 | CS | 5080600 | 2467 | 0.090 | -0.0460 | No | ||
| 5 | IDH1 | 1990021 | 2731 | 0.074 | -0.0545 | No | ||
| 6 | SDHC | 3140347 6100156 | 3120 | 0.055 | -0.0712 | No | ||
| 7 | ALDOC | 450121 610427 | 3427 | 0.044 | -0.0844 | No | ||
| 8 | OGDH | 3840333 6350100 | 5273 | 0.016 | -0.1825 | No | ||
| 9 | PKLR | 1170400 2470114 | 6390 | 0.009 | -0.2419 | No | ||
| 10 | PFKL | 6200167 | 6723 | 0.008 | -0.2592 | No | ||
| 11 | SUCLA2 | 730632 1170292 | 7431 | 0.005 | -0.2968 | No | ||
| 12 | ALDOB | 4730324 | 8087 | 0.003 | -0.3318 | No | ||
| 13 | PDHB | 70215 610086 | 9006 | 0.001 | -0.3811 | No | ||
| 14 | SDHA | 7000056 | 9885 | -0.001 | -0.4283 | No | ||
| 15 | GAPDHS | 2690463 | 10198 | -0.002 | -0.4449 | No | ||
| 16 | PDHX | 870315 | 10398 | -0.003 | -0.4554 | No | ||
| 17 | PGK2 | 2650091 | 10781 | -0.004 | -0.4757 | No | ||
| 18 | BPGM | 5080520 | 11595 | -0.007 | -0.5190 | No | ||
| 19 | MDH2 | 1850601 | 12591 | -0.011 | -0.5717 | No | ||
| 20 | MDH1 | 6660358 6760731 | 12846 | -0.012 | -0.5845 | No | ||
| 21 | FBP2 | 1580193 | 13817 | -0.020 | -0.6351 | No | ||
| 22 | ENO2 | 2320068 | 14205 | -0.025 | -0.6541 | No | ||
| 23 | DLAT | 430452 | 14734 | -0.034 | -0.6800 | No | ||
| 24 | ENO1 | 5340128 | 14984 | -0.040 | -0.6903 | No | ||
| 25 | AMAC1 | 940270 | 15437 | -0.054 | -0.7106 | No | ||
| 26 | PGAM2 | 3610605 | 15878 | -0.073 | -0.7287 | No | ||
| 27 | DLD | 4150403 6590341 | 16231 | -0.092 | -0.7407 | No | ||
| 28 | SDHB | 3120398 4780113 3710435 | 16306 | -0.098 | -0.7373 | No | ||
| 29 | PFKM | 1990156 5720168 | 16826 | -0.138 | -0.7548 | No | ||
| 30 | SDHD | 2570128 | 16873 | -0.143 | -0.7464 | No | ||
| 31 | PGAM1 | 2570133 | 17077 | -0.165 | -0.7448 | No | ||
| 32 | ACO1 | 50114 | 17650 | -0.270 | -0.7552 | Yes | ||
| 33 | ALDOA | 6290672 | 18195 | -0.486 | -0.7477 | Yes | ||
| 34 | PKM2 | 6520403 70500 | 18229 | -0.514 | -0.7106 | Yes | ||
| 35 | FBP1 | 1470762 | 18434 | -0.818 | -0.6597 | Yes | ||
| 36 | ENO3 | 5270136 | 18453 | -0.871 | -0.5947 | Yes | ||
| 37 | TPI1 | 1500215 2100154 | 18514 | -1.197 | -0.5073 | Yes | ||
| 38 | PFKP | 70138 6760040 1170278 | 18572 | -1.792 | -0.3748 | Yes | ||
| 39 | PGK1 | 1570494 630300 | 18612 | -4.983 | 0.0002 | Yes |
